Oxyhemoglobin, R state
Human hemoglobin in the oxygen-bound R state. The classic structure that captures cooperative binding mid-cycle.
JTJin Tanaka
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Human hemoglobin in the oxygen-bound R state. The classic structure that captures cooperative binding mid-cycle.
β2 adrenergic receptor captured coupled to its heterotrimeric Gs partner. A landmark GPCR signaling complex.
Human deoxyhemoglobin in the tense T state. Pairs naturally with 1HHO to study the allosteric switch behind cooperative oxygen binding.
Src tyrosine kinase in its closed, autoinhibited conformation — the regulatory baseline that activation has to overcome.