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Hen egg-white lysozyme

Classic 129-residue enzyme that cleaves bacterial cell walls. A long-standing benchmark for force-field validation and protein dynamics.

EnzymeLysozymes1AKI
Source: RCSB PDB

CRISPR-Cas9 with sgRNA and DNA

Cas9 bound to a single-guide RNA and target DNA. The complete editing complex in a cleavage-ready geometry.

EnzymeCRISPR-Cas94OO8
Source: RCSB PDB

Src tyrosine kinase, autoinhibited

Src tyrosine kinase in its closed, autoinhibited conformation — the regulatory baseline that activation has to overcome.

EnzymeKinases2SRC
Source: RCSB PDB

Protein kinase A, catalytic subunit

PKA catalytic subunit bound to ATP and substrate peptide — the textbook reference structure for protein kinases.

EnzymeKinases1ATP
Source: RCSB PDB