CRISPR-Cas9 with sgRNA and DNA
Cas9 bound to a single-guide RNA and target DNA. The complete editing complex in a cleavage-ready geometry.
MAMarcus Adebayo
000
Ask anything about this simulation. Answers are grounded in the listed sources — no free-form invention.
Classic 129-residue enzyme that cleaves bacterial cell walls. A long-standing benchmark for force-field validation and protein dynamics.
Other simulations in Lysozymes.
Cas9 bound to a single-guide RNA and target DNA. The complete editing complex in a cleavage-ready geometry.
PKA catalytic subunit bound to ATP and substrate peptide — the textbook reference structure for protein kinases.
Src tyrosine kinase in its closed, autoinhibited conformation — the regulatory baseline that activation has to overcome.
Comments coming soon
Phase 7 will add discussion threads